Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307530 | 1.00 | TSHR (0.39) | TSHRFAAHTRPV1L3MBTL1F7 | |
| SCHEMBL9326584 | 0.98 | L3MBTL1 (0.38) | TSHRFAAHTRPV1L3MBTL1F7 | |
| SCHEMBL3310877 | 0.98 | L3MBTL1 (0.38) | TSHRFAAHTRPV1L3MBTL1F7 | |
| SCHEMBL9326645 | 0.91 | FAAH (0.43) | TSHRFAAHTRPV1L3MBTL1MEN1 | |
| SCHEMBL9225054 | 0.90 | FAAH (0.47) | TSHRFAAHTRPV1 | |
| SCHEMBL9325532 | 0.90 | FAAH (0.47) | TSHRFAAHTRPV1 | |
| SCHEMBL9328599 | 0.90 | FAAH (0.47) | TSHRFAAHTRPV1 | |
| SCHEMBL9325631 | 0.90 | FAAH (0.47) | TSHRFAAHTRPV1 | |
| SCHEMBL8023741 | 0.90 | FAAH (0.47) | TSHRFAAHTRPV1 | |
| SCHEMBL9225064 | 0.90 | FAAH (0.47) | TSHRFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987232-A | ONE POT, GOOD YIELD | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B.V. (NL) | 1991-01-22 | — | — | US | disclosed |
| EP-0372654-A2 | Preparation of 2-chloropyridine 3-carboxylic acid esters | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-06-13 | — | — | EP | disclosed |
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |