Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 2/20 | 0.65 |
| ▸ | HTR2C | P28335 | 2/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870507 | 0.92 | DRD2 (0.55) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL7379763 | 0.87 | MEN1 (0.70) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9870458 | 0.81 | DRD2 (0.54) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL7358803 | 0.79 | SIGMAR1 (1.00) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9870722 | 0.78 | DRD2 (0.52) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9870941 | 0.78 | DRD2 (0.57) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| Bromide SCHEMBL467156 | 0.78 | SIGMAR1 (1.00) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL7383749 | 0.77 | DRD2 (0.56) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9871169 | 0.77 | DRD2 (0.67) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| Maleic Acid SCHEMBL8555257 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077288-A | Adrenergic, serotonin and histamine antagonist | ADIR ET COMPAGNIE (FR) | 1991-12-31 | — | — | US | disclosed |