Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870819 | 0.94 | KMT2A (0.51) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9872824 | 0.83 | HTR2A (0.56) | HTR2AHTR2CMEN1KMT2ACYP2D6 | |
| SCHEMBL9870723 | 0.78 | DRD2 (0.65) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9630470 | 0.78 | MEN1 (0.45) | MEN1KMT2ACYP2D6 | |
| SCHEMBL8557302 | 0.78 | DRD2 (0.54) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9630285 | 0.78 | OPRM1 (0.44) | DRD2HTR2AHTR2CSIGMAR1MEN1 | |
| SCHEMBL10963542 | 0.77 | HTR2A (0.54) | HTR2AHTR2CKCNH2CYP2D6 | |
| SCHEMBL7379763 | 0.76 | MEN1 (0.70) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL1156727 | 0.73 | KMT2A (0.49) | MEN1KMT2A | |
| SCHEMBL7383749 | 0.73 | DRD2 (0.56) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077288-A | Adrenergic, serotonin and histamine antagonist | ADIR ET COMPAGNIE (FR) | 1991-12-31 | — | — | US | disclosed |