SCHEMBL9871045

SCHEMBL9871045

CCN(CC)c1ccc(N(C(C)=S)c2ccccc2C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
RAB9A P51151 3/20 0.40
KMT2A Q03164 3/20 0.40
NPC1 O15118 2/20 0.40
NOX1 Q9Y5S8 1/20 0.40
CNR2 P34972 1/20 0.39
ALDH1A1 P00352 8/20 0.39
MAPT P10636 4/20 0.39
KDM4E B2RXH2 3/20 0.39
GAA P10253 3/20 0.39
MAPK1 P28482 2/20 0.39
HTT P42858 2/20 0.39
THRB P10828 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPSR1 Q6W5P4 1/20 0.38
CYP3A4 P08684 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
TSHR P16473 3/20 0.38
PSMD14 O00487 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9871684 0.81 NQO1 (0.40) RAB9ANPC1ALDH1A1MAPTMAPK1
SCHEMBL9870757 0.79 LMNA (0.41) MEN1RAB9AKMT2ANPC1ALDH1A1
SCHEMBL328909 0.71 CYP3A4 (0.46) RAB9ANPC1CNR2ALDH1A1MAPT
SCHEMBL29520654 0.71 CYP3A4 (0.46) RAB9ANPC1CNR2ALDH1A1MAPT
SCHEMBL610064 0.70 MAPT (0.51) MEN1RAB9AKMT2ANPC1NOX1
Lithium Ion SCHEMBL19732706 0.69 CYP3A4 (0.44) RAB9ANPC1CNR2ALDH1A1MAPT
SCHEMBL21065758 0.69 CYP3A4 (0.44) RAB9ANPC1CNR2ALDH1A1MAPT
SCHEMBL17956796 0.68 ALDH1A1 (0.64) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL14354423 0.68 ALDH1A1 (0.44) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL16577642 0.68 CYP3A4 (0.43) MEN1KMT2ACNR2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5019611-A Tetrahydrotriazinethiones THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-05-28 US disclosed