Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | TERT | O14746 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385477 | 0.90 | KMT2A (0.49) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9384406 | 0.87 | LMNA (0.61) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9429270 | 0.86 | TP53 (0.60) | LMNAALDH1A1TERTMEN1KMT2A | |
| Oxalic Acid SCHEMBL9384506 | 0.85 | LMNA (0.57) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9385273 | 0.81 | HRH3 (0.60) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9388604 | 0.81 | KMT2A (0.60) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9870792 | 0.80 | SMN1; SMN2 (0.50) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4746764 | 0.80 | LMNA (0.75) | LMNAALDH1A1TERTMEN1KMT2A | |
| SCHEMBL9384842 | 0.79 | KCNJ1 (0.58) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4749971 | 0.79 | LMNA (0.73) | LMNAALDH1A1TERTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |