Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870796 | 0.90 | LMNA (0.50) | KMT2ALMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL9384406 | 0.88 | LMNA (0.61) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9428233 | 0.86 | CACNA1G (0.57) | LMNAALDH1A1CACNA1GGAAHTR1A | |
| Oxalic Acid SCHEMBL9384506 | 0.85 | LMNA (0.57) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9388850 | 0.83 | KMT2A (0.48) | KMT2ALMNAMAPTSMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL9383787 | 0.82 | KMT2A (0.47) | KMT2ALMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL9384376 | 0.81 | KCNJ1 (0.58) | KMT2AALDH1A1MEN1HRH1 | |
| Hydrochloric Acid SCHEMBL9384359 | 0.80 | KCNJ1 (0.57) | KMT2AALDH1A1MEN1HRH1 | |
| SCHEMBL9388604 | 0.80 | KMT2A (0.60) | KMT2AMAPTALDH1A1HTR1AHTR7 | |
| SCHEMBL9385412 | 0.80 | HRH3 (0.62) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |