Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429265 | 0.87 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9870796 | 0.80 | LMNA (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9384406 | 0.79 | LMNA (0.61) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9385637 | 0.78 | LMNA (0.61) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28304755 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| Oxalic Acid SCHEMBL9384506 | 0.76 | LMNA (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9385477 | 0.76 | KMT2A (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9385398 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9384016 | 0.74 | SIRT6 (0.60) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| Oxalic Acid SCHEMBL9389932 | 0.73 | TDP1 (0.41) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |