Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 known ✓ | P35367 | 13/20 | 0.41 |
| ▸ | HRH2 | P25021 | 20/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 16/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL7275463 | 0.90 | CYP1A2 (0.44) | HRH2HRH4HRH3HRH1DRD2 | |
| Cadaverine Tartrate SCHEMBL9870481 | 0.86 | CYP1A2 (0.46) | — | |
| Hydrochloric Acid SCHEMBL7270360 | 0.77 | ALDH1A1 (0.44) | — | |
| SCHEMBL7270078 | 0.76 | ALDH1A1 (0.48) | — | |
| Cadaverine Tartrate SCHEMBL9870835 | 0.75 | PARP1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL7393597 | 0.75 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL9871841 | 0.72 | HTT (0.49) | — | |
| Hydrochloric Acid SCHEMBL9143272 | 0.72 | HTR2C (0.30) | — | |
| Hydrochloric Acid SCHEMBL7319036 | 0.71 | ATM (0.43) | HRH2HRH4HRH3HRH1DRD2 | |
| SCHEMBL9872432 | 0.71 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071864-A | Administering for high blood pressure and central nervous syst em disorders | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |