Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871105 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL9871630 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL9871903 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL25137411 | 0.76 | LMNA (0.59) | MAPTALDH1A1GAAMAPK1HTT | |
| SCHEMBL9872614 | 0.76 | FAAH (0.46) | MAPTALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL1735497 | 0.72 | ALDH1A1 (0.74) | MAPTALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL9872327 | 0.71 | MAPT (0.48) | MAPTALDH1A1GAAMAPK1HTT | |
| SCHEMBL9871294 | 0.71 | RAB9A (0.52) | MAPTALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL8772730 | 0.71 | MAPT (0.65) | MAPTALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL611209 | 0.70 | ALDH1A1 (0.52) | MAPTALDH1A1GAAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |