Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765398 | 0.83 | SMN1; SMN2 (0.44) | MGLLFAAHALDH1A1MAPTCYP2C19 | |
| SCHEMBL9528416 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL4913725 | 0.80 | TSHR (0.67) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL8601502 | 0.76 | PHGDH (0.59) | MGLLFAAHNCOA3ALDH1A1MAPT | |
| SCHEMBL13433496 | 0.76 | PKM (0.49) | MGLLFAAHNCOA3ALDH1A1MAPT | |
| SCHEMBL10458916 | 0.72 | CA12 (0.50) | MGLLFAAHALDH1A1MAPTPHGDH | |
| Morpholino(Phenyl)Methanethione SCHEMBL9180076 | 0.71 | MGLL (0.79) | MGLLFAAHNCOA3ALDH1A1MAPT | |
| SCHEMBL8662309 | 0.70 | TSHR (0.56) | MGLLFAAHNCOA3ALDH1A1PHGDH | |
| SCHEMBL27544096 | 0.70 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL10154719 | 0.70 | SMN1; SMN2 (0.57) | ALDH1A1MAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | claimed |
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |