SCHEMBL9871371

SCHEMBL9871371

[CH2]CCOC(C)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.43
SCN1A P35498 3/20 0.40
SCN2A Q99250 3/20 0.40
SCN3A Q9NY46 3/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
CYP1A2 P05177 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
ADRA2A P08913 1/20 0.40
CYP2D6 P10635 1/20 0.40
CHRM1 P11229 1/20 0.40
TSHR P16473 1/20 0.40
ADRA2B P18089 1/20 0.40
CHRM3 P20309 1/20 0.40
SLC6A2 P23975 1/20 0.40
HRH2 P25021 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7800154 0.88 ALDH1A1 (0.41) TAAR1SCN1ASCN2ASCN3ALMNA
SCHEMBL17305906 0.83 SLC6A2 (0.46) SCN1ASCN2ASCN3ALMNAHTT
SCHEMBL293762 0.83 TAAR1 (0.43) TAAR1SCN1ASCN2ASCN3ALMNA
SCHEMBL431888 0.81 SCN1A (0.41) TAAR1SCN1ASCN2ASCN3ALMNA
SCHEMBL2701953 0.81 HTT (0.42) TAAR1SCN1ASCN2ASCN3ALMNA
SCHEMBL97126 0.79 HCAR2 (0.41) TAAR1SCN1ASCN2ASCN3ALMNA
SCHEMBL29633537 0.79 TRPA1 (0.44) SCN1ASCN2ASCN3ALMNAHTT
SCHEMBL584471 0.79 ADRA2A (0.42) TAAR1SCN1ASCN2ASCN3ALMNA
SCHEMBL19368242 0.79 HPGD (0.41) TAAR1SCN1ASCN2ASCN3ALMNA
SCHEMBL97127 0.79 TRPA1 (0.44) SCN1ASCN2ASCN3ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5076829-A SUBSTITUTED 2,3-EPOXY-5-CYCLOHEXENONE DERIVATIVES, AND FUNGICIDES AND HERBICIDES CONTAINING SAME BASF AKTIENGESELLSCHAFT (DE) 1991-12-31 US disclosed
EP-0282792-B1 SUBSTITUTED 2,3-EPOXY-5-CYCLOHEXENONE DERIVATIVES AND FUNGICIDES AND HERBICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1990-05-30 EP disclosed
EP-0282792-A1 Substituted 2,3-epoxy-5-cyclohexenone derivatives and fungicides and herbicides containing them BASF Aktiengesellschaft (DE) 1988-09-21 EP disclosed