Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633537 | 1.00 | TRPA1 (0.44) | TRPA1ALDH1A1KDM4ERECQLCYP2D6 | |
| SCHEMBL21072047 | 0.89 | MEN1 (0.40) | TRPA1ALDH1A1RECQLCYP2D6SLC6A2 | |
| SCHEMBL14813927 | 0.88 | ALDH1A1 (0.44) | TRPA1ALDH1A1KDM4ECYP2D6SLC6A2 | |
| SCHEMBL9234762 | 0.86 | UGCG (0.44) | TRPA1ALDH1A1KDM4ECYP2D6SLC6A2 | |
| SCHEMBL2701953 | 0.85 | HTT (0.42) | KDM4ECYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6267450 | 0.83 | TRPA1 (0.45) | TRPA1ALDH1A1KDM4EADRA2ALMNA | |
| SCHEMBL431888 | 0.81 | SCN1A (0.41) | ALDH1A1KDM4ECYP2D6SLC6A2SLC6A4 | |
| Di(Hydroxyethyl)Ether SCHEMBL11297509 | 0.80 | TRPA1 (0.42) | TRPA1ALDH1A1KDM4ERECQLCYP2D6 | |
| SCHEMBL27883397 | 0.80 | LMNA (0.43) | KDM4ECYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9619657 | 0.80 | CYP2D6 (0.50) | TRPA1ALDH1A1KDM4ERECQLCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348438-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-02 | — | — | US | disclosed |
| US-20200317644-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2020-10-08 | — | — | US | disclosed |
| EP-3524599-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2019-08-14 | — | — | EP | disclosed |
| US-20180346449-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2018-12-06 | — | — | US | disclosed |
| US-9777020-B2 | Furo-3-carboxamide derivatives and methods of use | ABBVIE INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-20150210720-A1 | FURO-3-CARBOXAMIDE DERIVATIVES AND METHODS OF USE | ABBVIE INC. | 2015-07-30 | — | — | US | disclosed |
| US-20150183763-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2015-07-02 | — | — | US | disclosed |
| EP-2784074-A1 | PYRAZOLE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | Japan Tobacco, Inc. (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-8846746-B2 | Pyrazole compound and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2014-09-30 | — | — | US | disclosed |
| US-8586614-B2 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2013-11-19 | — | — | US | disclosed |
| US-5868511-A | AUTOLYOPHOBIC PROPERTIES OF INK IN PEN ALLOW THE TIP HOLDER TO BE SCARCELY WETTED WITH INK DURING ROTATION, SO BLOBBING DECREASES, AND LUBRICATING PROPERTIES IMPROVED FOR LESS WEAR ON THE TIP AND SMOOTH LIGHT WRITING FEEL | MITSUBISHI PENCIL KABUSHIKI KAISHA (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0702066-A2 | Non-aqueous ink for ball point pen, and ball point pen | MITSUBISHI PENCIL KABUSHIKI KAISHA (JP) | 1996-03-20 | — | — | EP | disclosed |
| EP-0393607-B1 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMA CO LTD (JP) | 1996-02-21 | — | — | EP | disclosed |
| US-5145865-A | Fatty acid, cholesterol synthesis inhibitors; enzyme inhibitors; antilipemic agents | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| US-4584396-A | Substituted phenoxypropionates and herbicidal compositions | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0086392-B1 | HERBICIDAL AGENT CONTAINING METAMITRON IN COMBINATION WITH CERTAIN PHENOXYPROPIONIC-ACID ESTERS | BAYER AG (DE) | 1985-08-21 | — | — | EP | disclosed |
| US-4441913-A | PRE- AND POST-EMERGENCE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-10 | — | — | US | disclosed |
| EP-0086392-A1 | Herbicidal agent containing metamitron in combination with certain phenoxypropionic-acid esters | BAYER AG (DE) | 1983-08-24 | — | — | EP | disclosed |
| EP-0084819-A2 | Herbicidal agents containing methabenzthiazuron in combination with certain phenoxypropionic acid esters | BAYER AG (DE) | 1983-08-03 | — | — | EP | disclosed |
| EP-0068260-A2 | Substituted phenoxypropionates, process for their preparation and their use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180346449-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | CYP2C19, CYP3A7, CYP3A5 | TRPA1 620/4885ALDH1A1 1200/4885KDM4E 4198/4885 |
| US-20230348438-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | CYP2C19, CYP3A7, CYP3A5 | TRPA1 620/4885ALDH1A1 1200/4885KDM4E 4198/4885 |
| US-20150210720-A1 | FURO-3-CARBOXAMIDE DERIVATIVES AND METHODS OF USE | NTRK2, MUSK, NTRK3 | TRPA1 2238/4885ALDH1A1 2033/4885KDM4E 3397/4885 |
| US-20200317644-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | CYP2C19, CYP3A7, CYP3A5 | TRPA1 620/4885ALDH1A1 1200/4885KDM4E 4198/4885 |
| US-20150183763-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | SLC5A1, SLC5A2, SLC34A1 | TRPA1 321/4885ALDH1A1 676/4885KDM4E 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.