Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 9/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | POLR1A | O95602 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752566 | 0.81 | PDE4B (0.58) | PDE4BPDE4DACP1HRH3 | |
| SCHEMBL9871656 | 0.80 | ACHE (0.46) | PDE4BPDE4DRAB9APOLR1A | |
| SCHEMBL9870693 | 0.80 | PDE4B (0.58) | PDE4BPDE4DACP1HRH3 | |
| SCHEMBL9871473 | 0.80 | PDE4B (0.55) | PDE4BPDE4DHRH3 | |
| SCHEMBL9870667 | 0.80 | PDE4B (0.45) | PDE4BPDE4DNPC1RAB9A | |
| SCHEMBL9870727 | 0.78 | LMNA (0.53) | PDE4BPDE4D | |
| SCHEMBL9752708 | 0.78 | PDE4B (0.44) | PDE4BPDE4DNPC1RAB9A | |
| SCHEMBL9752592 | 0.78 | PDE4B (0.47) | PDE4BPDE4D | |
| SCHEMBL9752995 | 0.78 | PDE4B (0.60) | PDE4BPDE4D | |
| Hydrochloric Acid SCHEMBL9752508 | 0.77 | PDE4B (0.43) | PDE4BPDE4DNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985560-A | Pyridazino(4,5-b)indolizines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-01-15 | — | — | US | disclosed |