SCHEMBL9871470

SCHEMBL9871470

CCCCOC(=O)Oc1c(-n2nc3ccccc3n2)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 4/20 0.36
PPARG P37231 3/20 0.36
ALDH1A1 P00352 5/20 0.35
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
L3MBTL1 Q9Y468 4/20 0.35
GAA P10253 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
XBP1 P17861 1/20 0.35
ATM Q13315 1/20 0.35
ELANE P08246 3/20 0.35
TDP1 Q9NUW8 3/20 0.34
TSHR P16473 1/20 0.34
PPARA Q07869 1/20 0.34
BCHE P06276 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10593219 0.84 VCAM1 (0.39) RXRAPPARGALDH1A1NPC1RAB9A
SCHEMBL9870748 0.82 VCAM1 (0.40) PPARGALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL9872313 0.81 NPC1 (0.50) PPARGALDH1A1NPC1RAB9ASMN1; SMN2
Naphthalene SCHEMBL9872543 0.78 RAB9A (0.47) PPARGALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL5417312 0.78 NPC1 (0.41) PPARGALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL28022693 0.77 NPC1 (0.38) RXRAPPARGALDH1A1NPC1RAB9A
SCHEMBL3537498 0.75 HTT (0.40) RXRAPPARGALDH1A1NPC1RAB9A
SCHEMBL10684710 0.74 NPC1 (0.34) PPARGALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL9879793 0.74 VCAM1 (0.36) SMN1; SMN2HPGDKMT2A
SCHEMBL9872532 0.73 L3MBTL1 (0.43) ALDH1A1L3MBTL1ATMTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5030731-A Substituted benzotriazoles; storage stability; lacquers CIBA-GEIGY CORPORATION (US) 1991-07-09 US disclosed
US-4775707-A BLOCKED BENZOTRIAZOLES CIBA-GEIGY CORPORATION (US) 1988-10-04 US disclosed
EP-0180548-A2 Coatings stabilized against the action of light CIBA-GEIGY AG (CH) 1986-05-07 EP disclosed