Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870526 | 0.83 | CHRM3 (0.36) | ALDH1A1KDM4EHPGDTSHRSMN1; SMN2 | |
| SCHEMBL9870662 | 0.74 | LMNA (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL8804810 | 0.73 | HSD17B10 (0.41) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL7955798 | 0.70 | HTR2A (0.44) | ALDH1A1HPGDSMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL11789560 | 0.66 | CYP1A2 (0.45) | ALDH1A1KDM4EHPGDTSHRSMN1; SMN2 | |
| SCHEMBL3218873 | 0.65 | NR1H2 (0.46) | ALDH1A1KDM4EPOLBKMT2ACYP1A2 | |
| SCHEMBL11840093 | 0.65 | CASP3 (0.47) | ALDH1A1KDM4EHPGDTSHRKMT2A | |
| SCHEMBL8174003 | 0.65 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2POLBKMT2A | |
| SCHEMBL7052087 | 0.65 | KMT2A (0.46) | POLBKMT2AGAA | |
| SCHEMBL23505970 | 0.64 | MAPT (0.47) | TSHRPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983613-A | Acetamides; treatment of neuropathy, nephropathy, retinopathy or cataracts in diabetic mammals | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-01-08 | — | — | US | claimed |
| US-4983613-A | Acetamides; treatment of neuropathy, nephropathy, retinopathy or cataracts in diabetic mammals | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-01-08 | — | — | US | disclosed |