Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870877 | 0.91 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDGAACASP1 | |
| SCHEMBL9871624 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL9870662 | 0.81 | LMNA (0.39) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL9384033 | 0.75 | ALDH1A1 (0.41) | CHRM3ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9684160 | 0.72 | AKR1B1 (0.42) | KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL11788765 | 0.69 | KDM4E (0.38) | ALDH1A1KDM4EHPGDGAACASP1 | |
| SCHEMBL8320575 | 0.68 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDGAACASP1 | |
| SCHEMBL11789702 | 0.65 | MEN1 (0.52) | GAALMNASMN1; SMN2MAPT | |
| SCHEMBL13493020 | 0.64 | CA1 (0.39) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL10153305 | 0.62 | MEN1 (0.46) | ALDH1A1GAASMN1; SMN2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983613-A | Acetamides; treatment of neuropathy, nephropathy, retinopathy or cataracts in diabetic mammals | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-01-08 | — | — | US | claimed |
| US-4983613-A | Acetamides; treatment of neuropathy, nephropathy, retinopathy or cataracts in diabetic mammals | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-01-08 | — | — | US | disclosed |