Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870854 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAKDM4ELMNA | |
| SCHEMBL9869833 | 0.78 | CACNA1F (0.42) | ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL9870706 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HSD17B10MAPTKMT2AGAA | |
| SCHEMBL9871298 | 0.74 | ATM (0.47) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL9869972 | 0.72 | ATM (0.43) | TSHRALDH1A1MAPTMEN1POLB | |
| SCHEMBL9871899 | 0.71 | CACNA1F (0.60) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL9870418 | 0.69 | GAA (0.47) | TSHRALDH1A1MAPTMEN1POLB | |
| SCHEMBL9871923 | 0.68 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4ELMNANPSR1 | |
| SCHEMBL9475138 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MAPTPOLBGAA | |
| SCHEMBL9870085 | 0.68 | GUSB (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071849-A | Antiinflammatory, antianginal agent | EGIS GYOGYSZERGYAR (HU) | 1991-12-10 | — | — | US | disclosed |