Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871923 | 0.88 | ALDH1A1 (0.54) | GUSBALDH1A1CA1CA2LMNA | |
| SCHEMBL9871999 | 0.85 | ALDH1A1 (0.47) | GUSBALDH1A1CA1CA2LMNA | |
| SCHEMBL9869503 | 0.81 | CACNA1F (0.44) | ALDH1A1CA1CA2LMNAMAPT | |
| SCHEMBL9871252 | 0.76 | CACNA1F (0.47) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL9869835 | 0.75 | CACNA1F (0.68) | GUSBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9870929 | 0.73 | CACNA1F (0.40) | GUSBALDH1A1CA1CA2CACNA1F | |
| SCHEMBL9870739 | 0.73 | ALDH1A1 (0.36) | ALDH1A1CA1CA2LMNAMAPT | |
| SCHEMBL9870764 | 0.72 | POLB (0.45) | ALDH1A1CA1CA2LMNAMAPT | |
| SCHEMBL9870854 | 0.71 | ALDH1A1 (0.43) | ALDH1A1CA1CA2LMNAMAPT | |
| SCHEMBL9870211 | 0.70 | ALDH1A1 (0.53) | GUSBALDH1A1CA1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071849-A | Antiinflammatory, antianginal agent | EGIS GYOGYSZERGYAR (HU) | 1991-12-10 | — | — | US | disclosed |