Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27572042 | 0.91 | MMP14 (0.47) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27590295 | 0.89 | MMP14 (0.46) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| SCHEMBL7919851 | 0.85 | CNR1 (0.55) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| SCHEMBL5690769 | 0.83 | FFAR1 (0.53) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| SCHEMBL3714135 | 0.83 | FFAR1 (0.53) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| SCHEMBL19788211 | 0.83 | KCNJ1 (0.48) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| SCHEMBL27571912 | 0.82 | L3MBTL1 (0.54) | ALDH1A1MEN1KMT2ALMNAGRM8 | |
| SCHEMBL9871396 | 0.81 | MAPT (0.56) | ALDH1A1MAPTKMT2ATDP1KDM4E | |
| SCHEMBL11126171 | 0.81 | CNR1 (0.62) | ALDH1A1MAPTMEN1KMT2ACNR1 | |
| SCHEMBL8646829 | 0.81 | ALDH1A1 (0.46) | ALDH1A1NPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102267923-B | Histone deacetylase inhibitors | Taibei Medical University | 2015-07-15 | — | — | CN | disclosed |
| CN-102267923-A | Histone deacetylase inhibitors | — | 2011-12-07 | — | — | CN | disclosed |
| US-5008285-A | Antiarthritic agent with low gastric irritability side effect | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0159684-B1 | (6,11-DIHYDRO-11-OXODIBENZ(B,E)OXEPINYL)PENTANOIC ACIDS AND DERIVATIVES, A PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4560701-A | ANTIINFLAMMATORY, ANALGESIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0159684-A2 | (6,11-Dihydro-11-oxodibenz(b,e)oxepinyl)pentanoic acids and derivatives, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-10-30 | — | — | EP | disclosed |
| EP-0118867-A2 | Substituted 4,10-dihydro-10-oxothieno benzoxepins, a method of preparing the same and intermediate thereof and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-09-19 | — | — | EP | disclosed |