Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873640 | 0.82 | DRD2 (0.47) | HTR2CHTR2ADRD2 | |
| SCHEMBL13648727 | 0.78 | DRD2 (0.62) | HTR2CHTR2ADRD2DRD4HTR1A | |
| SCHEMBL13648741 | 0.75 | DRD2 (0.60) | HTR2CHTR2ADRD2DRD4 | |
| SCHEMBL7812646 | 0.74 | HTR2C (0.60) | HTR2CHTR2ADRD2DRD4 | |
| SCHEMBL9205093 | 0.73 | HTR2C (0.52) | HTR2CHTR2ADRD2DRD4HTR1A | |
| SCHEMBL7783722 | 0.73 | DRD2 (0.58) | HTR2CHTR2ADRD2DRD4 | |
| SCHEMBL7792010 | 0.73 | DRD2 (0.58) | HTR2CHTR2ADRD2DRD4 | |
| SCHEMBL9773116 | 0.72 | DRD2 (0.56) | HTR2CHTR2ADRD2DRD4HTR1A | |
| SCHEMBL9773119 | 0.72 | DRD2 (0.56) | HTR2CHTR2ADRD2DRD4HTR1A | |
| SCHEMBL9871472 | 0.72 | HTR1A (0.53) | HTR2CHTR2ADRD2DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |