Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871472 | 0.90 | HTR1A (0.53) | DRD2HTR2CHTR2ADRD3 | |
| SCHEMBL9874353 | 0.85 | DRD2 (0.55) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9872977 | 0.83 | KDM4E (0.59) | LMNAPOLBMAPTTSHRMAPK1 | |
| Water SCHEMBL9874791 | 0.82 | KDM4E (0.58) | LMNAPOLBMAPTTSHRMAPK1 | |
| Water SCHEMBL9874788 | 0.82 | KDM4E (0.58) | LMNAPOLBMAPTTSHRMAPK1 | |
| SCHEMBL9872107 | 0.82 | HTR2C (0.50) | DRD2HTR2CHTR2A | |
| SCHEMBL9872326 | 0.82 | LMNA (0.47) | DRD2DRD3LMNAPOLBGAA | |
| Water SCHEMBL9874020 | 0.81 | LMNA (0.46) | DRD2DRD3LMNAPOLBGAA | |
| Water SCHEMBL9874025 | 0.81 | LMNA (0.46) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9873718 | 0.80 | LMNA (0.43) | DRD2DRD3LMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |