Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | DRD3 | P35462 | 6/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873640 | 0.90 | DRD2 (0.47) | DRD2DRD3HTR2CHTR2A | |
| SCHEMBL9874358 | 0.85 | DRD2 (0.58) | DRD2DRD3 | |
| SCHEMBL9872977 | 0.82 | KDM4E (0.59) | — | |
| Water SCHEMBL9874788 | 0.81 | KDM4E (0.58) | — | |
| Water SCHEMBL9874791 | 0.81 | KDM4E (0.58) | — | |
| SCHEMBL9872326 | 0.80 | LMNA (0.47) | DRD2DRD3 | |
| Water SCHEMBL9874025 | 0.79 | LMNA (0.46) | DRD2DRD3 | |
| Water SCHEMBL9874020 | 0.79 | LMNA (0.46) | DRD2DRD3 | |
| SCHEMBL9873677 | 0.76 | KDM4E (0.47) | — | |
| SCHEMBL9872533 | 0.75 | DRD2 (0.49) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |