Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | PPID | Q08752 | 2/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | PPIG | Q13427 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870605 | 0.86 | KMT2A (0.46) | KDM4EALDH1A1CYP1A2LMNACYP3A4 | |
| SCHEMBL9082982 | 0.84 | CCKBR (0.44) | ALDH1A1HTTCYP1A2LMNACYP3A4 | |
| SCHEMBL1206362 | 0.84 | CYP4F2 (0.47) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5670458 | 0.84 | ALDH1A1 (0.62) | KDM4EALDH1A1HTTCYP1A2LMNA | |
| SCHEMBL29069352 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL1349171 | 0.84 | GRIA4 (0.41) | KDM4EALDH1A1HTTLMNAKMT2A | |
| SCHEMBL5691331 | 0.84 | ALDH1A1 (0.62) | KDM4EALDH1A1HTTCYP1A2LMNA | |
| SCHEMBL9871396 | 0.80 | MAPT (0.56) | KDM4EALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL6238563 | 0.79 | PPID (0.48) | KDM4EALDH1A1HTTCYP1A2LMNA | |
| SCHEMBL16245592 | 0.79 | LMNA (0.45) | KDM4EALDH1A1HTTCYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008285-A | Antiarthritic agent with low gastric irritability side effect | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0159684-B1 | (6,11-DIHYDRO-11-OXODIBENZ(B,E)OXEPINYL)PENTANOIC ACIDS AND DERIVATIVES, A PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4560701-A | ANTIINFLAMMATORY, ANALGESIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0159684-A2 | (6,11-Dihydro-11-oxodibenz(b,e)oxepinyl)pentanoic acids and derivatives, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-10-30 | — | — | EP | disclosed |
| EP-0118867-A2 | Substituted 4,10-dihydro-10-oxothieno benzoxepins, a method of preparing the same and intermediate thereof and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-09-19 | — | — | EP | disclosed |