Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677573 | 0.85 | GAA (0.36) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL11169574 | 0.80 | CA2 (0.47) | CA1CA2CA4CA6CA12 | |
| SCHEMBL5268908 | 0.78 | NFE2L2 (0.38) | L3MBTL1KMT2ATDP1AKR1B1 | |
| SCHEMBL31259921 | 0.78 | NFE2L2 (0.38) | L3MBTL1KMT2ATDP1AKR1B1 | |
| SCHEMBL29693002 | 0.76 | KMT2A (0.43) | L3MBTL1MAPTKMT2ATDP1MEN1 | |
| SCHEMBL1124590 | 0.76 | HSD11B1 (0.40) | L3MBTL1AKR1B1 | |
| SCHEMBL11107609 | 0.76 | GAA (0.54) | CA1CA2CA4CA6L3MBTL1 | |
| SCHEMBL10747298 | 0.76 | LOX (0.36) | CA2LOXPOLBCA12CA9 | |
| SCHEMBL395353 | 0.76 | KMT2A (0.43) | L3MBTL1MAPTKMT2ATDP1MEN1 | |
| SCHEMBL10885567 | 0.76 | CDK2 (0.37) | CA1CA2CA4CA6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996208-A | Pesticidal thiazolopyrimidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| EP-0348746-A2 | Thiazolopyrimidine derivatives, process for their preparation and their use as pest control agents | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |