Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872794 | 0.85 | SOAT2 (0.46) | MAPK1LMNASMN1; SMN2 | |
| SCHEMBL9874162 | 0.76 | CYP1A2 (0.49) | SCN4AALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL1414347 | 0.72 | LMNA (0.57) | MAPK1ALDH1A1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1414300 | 0.71 | LMNA (0.55) | MAPK1ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL9133647 | 0.70 | AURKA (0.57) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30051979 | 0.70 | MAPT (0.67) | MAPK1SCN4AALDH1A1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL30900133 | 0.69 | LMNA (0.53) | ALDH1A1LMNACYP1A2HTTCYP2C9 | |
| SCHEMBL20561612 | 0.68 | HDAC6 (0.41) | MAPK1ALDH1A1LMNAHTTHDAC6 | |
| SCHEMBL3035928 | 0.67 | LMNA (0.62) | MAPK1ALDH1A1LMNATSHRRAB9A | |
| SCHEMBL5815057 | 0.67 | P2RX7 (0.74) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | claimed |
| US-5073565-A | Atherosclerosis, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |