Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873800 | 0.84 | AGTR2 (0.62) | — | |
| SCHEMBL9872436 | 0.81 | AGTR1 (0.52) | — | |
| SCHEMBL29840938 | 0.79 | TLR7 (0.63) | TLR7 | |
| SCHEMBL9872309 | 0.79 | AGTR2 (0.61) | — | |
| SCHEMBL32675801 | 0.78 | TLR7 (0.61) | TLR7 | |
| SCHEMBL29840981 | 0.78 | TLR7 (0.66) | TLR7 | |
| Hydrochloric Acid SCHEMBL30663254 | 0.77 | TLR7 (0.60) | TLR7 | |
| SCHEMBL9873410 | 0.77 | AGTR1 (0.50) | — | |
| SCHEMBL9871402 | 0.76 | AGTR2 (0.60) | — | |
| SCHEMBL9028849 | 0.76 | KMT2A (0.66) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |