SCHEMBL9872989

SCHEMBL9872989

[S]c1ccccc1-n1ncnn1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 6/20 0.34
HCRTR2 O43614 6/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14886184 0.75 ALDH1A1 (0.41) HCRTR1HCRTR2
SCHEMBL7242985 0.75 HCRTR2 (0.34) HCRTR1HCRTR2
SCHEMBL9158738 0.75 MGLL (0.39)
SCHEMBL1128641 0.75 KCNMA1 (0.42) HCRTR1HCRTR2
SCHEMBL28609006 0.73 HCRTR2 (0.42) HCRTR1HCRTR2
SCHEMBL14883257 0.71 FAAH (0.44) HCRTR1HCRTR2
SCHEMBL1724085 0.71 KDM4E (0.42) HCRTR1HCRTR2
SCHEMBL20357739 0.71 ALDH1A1 (0.36) HCRTR1HCRTR2
SCHEMBL12087397 0.69 HCRTR2 (0.40) HCRTR1HCRTR2
SCHEMBL31006109 0.69 CYP19A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5073574-A TETRAZOLYL SUBSTITUTED BENZONITRILES AND ANTI-TUMOR USE THEREOF CIBA-GEIGY CORPORATION (US) 1991-12-17 US disclosed