Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477938 | 0.89 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| Iodide SCHEMBL8067949 | 0.87 | MAPT (0.87) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| Iodide SCHEMBL9768656 | 0.87 | MAPT (0.87) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| Perchlorate SCHEMBL11638443 | 0.86 | MAPT (0.78) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL10949400 | 0.84 | MAPT (0.48) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL11597990 | 0.84 | MAPT (0.48) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL12821746 | 0.82 | KMT2A (0.98) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL12821744 | 0.82 | KMT2A (0.98) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| Iodide SCHEMBL5329489 | 0.81 | KMT2A (1.00) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| Iodide SCHEMBL5329486 | 0.81 | KMT2A (1.00) | MAPTALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003077-A | Having a cycloheptimidazole nucleus; photostability; methine bond having an auxochrome | FUJI PHOTO FILM CO., LTD. (JP) | 1991-03-26 | — | — | US | disclosed |
| US-4900648-A | RECORDING, ERASING USING LASER BEAM, METHINE DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1990-02-13 | — | — | US | disclosed |
| US-4814265-A | CONTAINING METHANE DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-03-21 | — | — | US | disclosed |