Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599602 | 0.86 | PPOX (0.45) | NPC1PPOXMAPTMAOAGAA | |
| SCHEMBL9684646 | 0.84 | L3MBTL1 (0.39) | NPC1PPOXMAPTMAOAKDM4E | |
| SCHEMBL9872059 | 0.83 | NPC1 (0.43) | NPC1PPOXMAPTMAOAGAA | |
| SCHEMBL8604315 | 0.80 | CSNK2A1 (0.49) | NPC1PPOXMAPTMAOAGAA | |
| SCHEMBL8599263 | 0.79 | GLA (0.50) | NPC1PPOXMAPTMAOAGAA | |
| SCHEMBL8602962 | 0.77 | SMN1; SMN2 (0.46) | NPC1PPOXMAOAMEN1HPGD | |
| SCHEMBL9873396 | 0.76 | NPC1 (0.36) | NPC1PPOXMAPTMAOAGAA | |
| SCHEMBL8876498 | 0.75 | GAA (0.44) | NPC1MAPTMAOAGAAALDH1A1 | |
| SCHEMBL8879337 | 0.75 | L3MBTL1 (0.48) | NPC1MAPTMAOAGAAKDM4E | |
| SCHEMBL9871713 | 0.75 | NPC1 (0.38) | NPC1PPOXMAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017213-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0351641-A1 | 1-Phenylpyrrole | NIHON BAYER AGROCHEM K.K. (JP) | 1990-01-24 | — | — | EP | disclosed |