Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | NCF1 | P14598 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684658 | 0.88 | L3MBTL1 (0.44) | L3MBTL1MAOANPC1MEN1USP2 | |
| SCHEMBL9873170 | 0.84 | NPC1 (0.37) | L3MBTL1MAOAPPOXNPC1CSNK2A1 | |
| SCHEMBL8604315 | 0.84 | CSNK2A1 (0.49) | MAOAPPOXNPC1CSNK2A1MEN1 | |
| SCHEMBL8599602 | 0.84 | PPOX (0.45) | L3MBTL1MAOAPPOXNPC1MEN1 | |
| SCHEMBL8599263 | 0.83 | GLA (0.50) | L3MBTL1MAOAPPOXNPC1CSNK2A1 | |
| SCHEMBL8879337 | 0.83 | L3MBTL1 (0.48) | L3MBTL1MAOANPC1MEN1USP2 | |
| SCHEMBL9873744 | 0.82 | MAOA (0.33) | L3MBTL1NCF1MAOAPPOXNPC1 | |
| SCHEMBL8602962 | 0.81 | SMN1; SMN2 (0.46) | MAOAPPOXNPC1CSNK2A1MEN1 | |
| SCHEMBL9873603 | 0.81 | ALDH1A1 (0.40) | L3MBTL1MAOAPPOXNPC1MEN1 | |
| SCHEMBL17543904 | 0.79 | HTR2C (0.44) | MAOANPC1CSNK2A1GLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118849-A | Arylamines intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | claimed |
| EP-0349748-B1 | SUBSTITUTED N-ARYL-NITROGEN CONTAINING HETEROCYCLES | BAYER AG (DE) | 1992-11-19 | — | — | EP | disclosed |
| US-5118849-A | Arylamines intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-5039334-A | Herbicidal and plant growth-regulating substituted N-aryl nitrogen heterocycles | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-13 | — | — | US | disclosed |
| EP-0349748-A1 | Substituted N-aryl-nitrogen containing heterocycles | BAYER AG (DE) | 1990-01-10 | — | — | EP | disclosed |