Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26628119 | 0.80 | CETP (0.57) | CETPPOLBCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL30977681 | 0.79 | TAS2R14 (0.55) | CETPPOLBCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL9457765 | 0.79 | TAS2R14 (0.55) | CETPPOLBCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL997250 | 0.77 | KDM4E (0.57) | CETPPOLBALDH1A1ATMMAPK1 | |
| SCHEMBL4453238 | 0.77 | PLK1 (0.52) | CETPPOLBCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL9874730 | 0.77 | CETP (0.46) | CETPPOLBCYP1A2CYP2C9ATM | |
| SCHEMBL30937617 | 0.74 | ALDH1A1 (0.41) | CETPPOLBCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL30525296 | 0.72 | CETP (0.59) | CETPPOLBCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL23060406 | 0.70 | POLB (0.58) | POLBCYP1A2CYP2C9ALDH1A1ATM | |
| SCHEMBL5706504 | 0.70 | CETP (0.71) | CETPPOLBCYP1A2CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |