Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453238 | 0.88 | PLK1 (0.52) | CETPPOLBCYP1A2CYP2C9PDK1 | |
| SCHEMBL26628119 | 0.82 | CETP (0.57) | CETPPOLBCYP1A2CYP2C9KDM4E | |
| SCHEMBL9457765 | 0.81 | TAS2R14 (0.55) | CETPPOLBCYP1A2CYP2C9PDK1 | |
| SCHEMBL30977681 | 0.81 | TAS2R14 (0.55) | CETPPOLBCYP1A2CYP2C9PDK1 | |
| SCHEMBL1995318 | 0.78 | THRB (0.48) | KDM4EMEN1KMT2ALMNAGAA | |
| SCHEMBL9874486 | 0.77 | MAPT (0.56) | MEN1KMT2APLK1PLK3LMNA | |
| SCHEMBL9875019 | 0.77 | MEN1 (0.56) | CYP1A2KDM4EMEN1KMT2APLK1 | |
| SCHEMBL9873262 | 0.77 | CETP (0.44) | CETPPOLBCYP1A2CYP2C9PDK1 | |
| SCHEMBL9872839 | 0.76 | RAB9A (0.59) | CYP1A2MEN1KMT2APLK1PLK3 | |
| SCHEMBL9872356 | 0.76 | SMN1; SMN2 (0.52) | KDM4EMEN1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |