Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875839 | 0.89 | RORC (0.40) | RORCTSHRCTSLCTSBCTSS | |
| SCHEMBL9873858 | 0.88 | RORC (0.42) | RORCTSHRCTSLCTSBCTSS | |
| SCHEMBL9873493 | 0.86 | RORC (0.40) | RORCTSHRCTSLCTSBCTSS | |
| SCHEMBL9873533 | 0.81 | RORC (0.35) | RORCCTSLCTSBCTSSTDP1 | |
| SCHEMBL9873530 | 0.81 | RORC (0.35) | RORCCTSLCTSBCTSSTDP1 | |
| SCHEMBL9875722 | 0.80 | RORC (0.35) | RORCTSHRCTSLCTSBCTSS | |
| SCHEMBL9874444 | 0.80 | RORC (0.35) | RORCTSHRCTSLCTSBCTSS | |
| SCHEMBL9874253 | 0.78 | RORC (0.43) | RORCTSHRCTSLCTSBCTSS | |
| SCHEMBL9872276 | 0.78 | RORC (0.41) | RORCCTSLCTSBCTSSTDP1 | |
| SCHEMBL9872800 | 0.77 | RORC (0.43) | RORCCTSLCTSBCTSSHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |