Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10451394 | 0.83 | LMNA (0.58) | MAPTALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL31474545 | 0.83 | EPHX2 (0.50) | MAPTALDH1A1MEN1KMT2ACTSB | |
| SCHEMBL8372261 | 0.83 | CYP1A2 (0.58) | CYP1A2TSHRNFKB1MAOBMAPT | |
| SCHEMBL14213496 | 0.82 | RAB9A (0.56) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL9827345 | 0.81 | CTSL (0.61) | ALDH1A1LMNAKMT2ARAB9ACTSB | |
| SCHEMBL17011384 | 0.81 | KDM4E (0.58) | TSHRMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL10764773 | 0.81 | CTSL (0.59) | ALDH1A1RAB9ACTSBNAMPTNPC1 | |
| SCHEMBL26261156 | 0.81 | MEN1 (0.62) | MAOBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18704329 | 0.81 | CA12 (0.63) | CYP1A2TSHRNFKB1MAOBMAPT | |
| SCHEMBL10645430 | 0.81 | RAB9A (0.54) | CYP1A2MEN1KMT2ACYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043467-A | Halogenating, quaternizing substituted N-cyanomethylamide; desalting; herbicides, fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-08-27 | — | — | US | disclosed |
| EP-0135304-B1 | PREPARATION OF SUBSTITUTED BENZAMIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-14 | — | — | EP | disclosed |
| US-4786747-A | BROMINATION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-11-22 | — | — | US | disclosed |
| EP-0260801-A2 | Process for the production of substituted amides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-23 | — | — | EP | disclosed |
| EP-0258631-A2 | Alkoxyimoalkylamides | BAYER AG (DE) | 1988-03-09 | — | — | EP | disclosed |
| EP-0149324-B1 | BIOLOGICALLY ACTIVE AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-02 | — | — | EP | disclosed |
| US-4663481-A | BROMINATION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-05 | — | — | US | disclosed |
| EP-0144177-B1 | PREPARATION OF BROMOACETAMIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-04 | — | — | EP | disclosed |
| US-4575557-A | ACETONITRILE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-03-11 | — | — | US | disclosed |
| EP-0149324-A2 | Biologically active amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-07-24 | — | — | EP | disclosed |
| EP-0144177-A1 | Preparation of bromoacetamides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-12 | — | — | EP | disclosed |
| EP-0135304-A2 | Preparation of substituted benzamides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-27 | — | — | EP | disclosed |