Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872913 | 0.78 | KMT2A (0.41) | CRHBPCRHR2ALDH1A1KMT2AKDM4E | |
| SCHEMBL9872562 | 0.77 | MAPK1 (0.39) | CRHBPCRHR2ALDH1A1KMT2AKDM4E | |
| SCHEMBL9873422 | 0.74 | KMT2A (0.38) | ALDH1A1KMT2AKDM4EHPGDTP53 | |
| SCHEMBL9873486 | 0.73 | TSHR (0.41) | CRHBPCRHR2ALDH1A1KDM4EHPGD | |
| SCHEMBL9874822 | 0.73 | TSHR (0.50) | ALDH1A1KMT2AKDM4ELMNAESR1 | |
| SCHEMBL9875296 | 0.71 | CRHBP (0.60) | CRHBPCRHR2ALDH1A1KMT2AKDM4E | |
| SCHEMBL4911331 | 0.70 | CRHBP (0.69) | CRHBPCRHR2ALDH1A1KLK7ESR1 | |
| SCHEMBL9314235 | 0.69 | CRHBP (0.46) | CRHBPCRHR2KDM4EKLK7TSHR | |
| SCHEMBL11000173 | 0.69 | KMT2A (0.57) | CRHBPCRHR2ALDH1A1KMT2AKDM4E | |
| SCHEMBL5402590 | 0.69 | CRHBP (0.54) | CRHBPCRHR2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |