Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873671 | 0.78 | CRHBP (0.45) | KMT2ATP53ESR1ESR2ALDH1A1 | |
| SCHEMBL9873422 | 0.76 | KMT2A (0.38) | KMT2ATP53ESR1ESR2ALDH1A1 | |
| SCHEMBL9872562 | 0.76 | MAPK1 (0.39) | KMT2ATP53ESR1ESR2ALDH1A1 | |
| SCHEMBL9875016 | 0.74 | TDP1 (0.42) | TP53ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9873418 | 0.73 | TSHR (0.47) | ESR1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL4909076 | 0.72 | ESR1 (0.51) | TP53ESR1ESR2ALDH1A1KDM4E | |
| SCHEMBL11000173 | 0.71 | KMT2A (0.57) | KMT2AESR1ESR2ALDH1A1KDM4E | |
| SCHEMBL1131746 | 0.70 | ESR1 (0.49) | KMT2AESR1ESR2ALDH1A1KDM4E | |
| SCHEMBL505248 | 0.69 | LMNA (0.57) | KMT2ATP53ALDH1A1LMNAHPGD | |
| SCHEMBL13545931 | 0.69 | ESR1 (0.72) | KMT2AESR1ESR2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |