Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872674 | 0.84 | ALDH1A1 (0.45) | KMT2AALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL9873291 | 0.75 | KMT2A (0.45) | KMT2AALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL9875232 | 0.75 | GRM4 (0.39) | KMT2AGRM4SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL9874916 | 0.75 | SMN1; SMN2 (0.42) | KMT2AALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL9874891 | 0.74 | HTT (0.54) | KMT2AALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL9545028 | 0.73 | KMT2A (0.54) | KMT2AALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL11807194 | 0.73 | PARP1 (0.62) | KMT2AALDH1A1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL29761118 | 0.73 | PARP1 (0.62) | KMT2AALDH1A1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL3709112 | 0.73 | SMN1; SMN2 (0.67) | KMT2AALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9874612 | 0.72 | MEN1 (0.62) | KMT2AALDH1A1HTTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |