Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381137 | 0.81 | GABRP (0.39) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL9874472 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL9874920 | 0.79 | TDP1 (0.47) | MEN1KMT2ALMNAHPGDCYP1A2 | |
| SCHEMBL9873674 | 0.75 | KMT2A (0.42) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL9872674 | 0.71 | ALDH1A1 (0.45) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL9387220 | 0.69 | GABRP (0.43) | SMN1; SMN2MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL9875417 | 0.68 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ALMNAGABRP | |
| SCHEMBL9381144 | 0.68 | HTT (0.40) | MEN1KMT2AHSD17B10L3MBTL1GPBAR1 | |
| SCHEMBL12550518 | 0.67 | POLB (0.50) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL2143821 | 0.65 | EGLN1 (0.57) | SMN1; SMN2MEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |