Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CATSPER1 | Q8NEC5 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873674 | 0.75 | KMT2A (0.42) | GRM4KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30380075 | 0.70 | KDM4E (0.44) | KMT2ACYP2C9DHODHLMNASMN1; SMN2 | |
| SCHEMBL3709112 | 0.69 | SMN1; SMN2 (0.67) | KMT2ACYP1A2CYP2C9CYP2C19DHODH | |
| SCHEMBL187899 | 0.67 | ALDH1A1 (0.55) | KMT2ADHODHLMNASMN1; SMN2AKR1C3 | |
| SCHEMBL11807194 | 0.66 | PARP1 (0.62) | KMT2ADHODHLMNASMN1; SMN2COMT | |
| SCHEMBL29761118 | 0.66 | PARP1 (0.62) | KMT2ADHODHLMNASMN1; SMN2COMT | |
| SCHEMBL27266845 | 0.66 | P2RX7 (0.54) | KMT2ADHODHCOMTAKR1C3MEN1 | |
| SCHEMBL30592534 | 0.66 | P2RX7 (0.54) | KMT2ADHODHCOMTAKR1C3MEN1 | |
| SCHEMBL296670 | 0.66 | KDM4E (0.69) | KMT2ACYP1A2DHODHLMNASMN1; SMN2 | |
| SCHEMBL8581405 | 0.66 | GLA (0.53) | KMT2ADHODHLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |