SCHEMBL10685486

SCHEMBL10685486

Nc1cc(OCC2CC2(Cl)Cl)c(Cl)cc1F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 18/20 0.33
SCN5A Q14524 2/20 0.31
NPC1 O15118 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10577542 0.88 NPC1 (0.34) SCN9ASCN5ANPC1
SCHEMBL9873759 0.80 FFAR4 (0.44) SCN9AFFAR4
SCHEMBL11042877 0.76 MRGPRX4 (0.38)
SCHEMBL30780907 0.74 SCN9A (0.46) SCN9ASCN5AFFAR4
SCHEMBL27267930 0.74 SCN9A (0.46) SCN9ASCN5AFFAR4
SCHEMBL10574877 0.73 SCN9A (0.34) SCN9A
SCHEMBL8599602 0.73 PPOX (0.45) NPC1
Hydrochloric Acid SCHEMBL10575002 0.72 SCN9A (0.34) SCN9A
SCHEMBL9685952 0.72 CA2 (0.40)
SCHEMBL9871713 0.72 NPC1 (0.38) NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268797-A2 Halogencyclopropyl compounds, their preparation and herbicidal application SCHERING AKTIENGESELLSCHAFT (DE) 1988-06-01 EP disclosed