SCHEMBL6577955

SCHEMBL6577955

CCCOc1ccccc1OC(=O)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
LMNA P02545 3/20 0.45
ALDH1A1 P00352 3/20 0.45
HIF1A Q16665 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
GLA P06280 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
POLB P06746 1/20 0.43
CASP6 P55212 1/20 0.43
MAPT P10636 3/20 0.42
MTNR1A P48039 2/20 0.42
MTNR1B P49286 2/20 0.42
FAAH O00519 6/20 0.42
THRB P10828 1/20 0.42
HPGD P15428 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706280 0.85 FAAH (0.55) KMT2ALMNAL3MBTL1NPC1RAB9A
SCHEMBL6575493 0.83 CYP1A2 (0.55) KMT2AMEN1LMNAALDH1A1HIF1A
SCHEMBL9874009 0.83 LMNA (0.50) KMT2AMEN1LMNAALDH1A1HIF1A
SCHEMBL898711 0.81 LMNA (0.59) KMT2AMEN1LMNAALDH1A1L3MBTL1
SCHEMBL4342476 0.81 BCHE (0.42) KMT2AMEN1LMNAALDH1A1HIF1A
SCHEMBL5155893 0.81 ALDH1A1 (0.50) KMT2AMEN1LMNAALDH1A1HIF1A
SCHEMBL9656386 0.81 KMT2A (0.42) KMT2AMEN1LMNAALDH1A1HIF1A
SCHEMBL9659104 0.81 KMT2A (0.42) KMT2AMEN1LMNAALDH1A1POLB
SCHEMBL9873999 0.80 NPC1 (0.48) KMT2AMEN1LMNAALDH1A1HIF1A
SCHEMBL26125296 0.79 ALDH1A1 (0.55) KMT2AMEN1LMNAALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed