Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468664 | 0.83 | CES2 (0.58) | CES2SRD5A2MAOB | |
| SCHEMBL9468665 | 0.83 | CES2 (0.58) | CES2SRD5A2MAOB | |
| SCHEMBL13729327 | 0.79 | CES2 (0.53) | CES2CES1 | |
| SCHEMBL6640583 | 0.77 | CYP11B1 (0.56) | CYP11B1CYP11B2CES2CES1NR4A1 | |
| SCHEMBL6640581 | 0.77 | CYP11B1 (0.56) | CYP11B1CYP11B2CES2CES1NR4A1 | |
| SCHEMBL3408557 | 0.76 | NPSR1 (0.55) | CYP11B1CYP11B2CES2CES1CYP1A1 | |
| SCHEMBL3408555 | 0.76 | NPSR1 (0.55) | CYP11B1CYP11B2CES2CES1CYP1A1 | |
| SCHEMBL9874152 | 0.74 | LMNA (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL9874146 | 0.74 | LMNA (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL17927021 | 0.73 | CYP11B1 (0.51) | CYP11B1CYP11B2CES2CES1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5022915-A | Substituted 2,4-diarylpyrimidines and their use as herbicides | ICI AMERICAS INC. (US) | 1991-06-11 | — | — | US | disclosed |