Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875116 | 0.80 | GAA (0.44) | GAARXFP1NPSR1MAPK1KMT2A | |
| SCHEMBL9874892 | 0.78 | GAA (0.53) | GAARXFP1NPSR1MAPK1KMT2A | |
| SCHEMBL9875111 | 0.76 | GAA (0.44) | GAARXFP1NPSR1MAPK1KMT2A | |
| SCHEMBL9875153 | 0.76 | PDE5A (0.53) | GAARXFP1NPSR1MAPK1KMT2A | |
| SCHEMBL9872808 | 0.72 | KMT2A (0.40) | GAARXFP1NPSR1KMT2AMEN1 | |
| SCHEMBL9873231 | 0.72 | KMT2A (0.50) | GAARXFP1NPSR1MAPK1KMT2A | |
| SCHEMBL10679446 | 0.69 | MAPK1 (0.70) | GAARXFP1NPSR1MAPK1KMT2A | |
| SCHEMBL23727276 | 0.68 | NPSR1 (0.44) | GAARXFP1NPSR1MAPK1KMT2A | |
| SCHEMBL30121511 | 0.68 | NPSR1 (0.44) | GAARXFP1NPSR1MAPK1KMT2A | |
| SCHEMBL30071633 | 0.68 | NPSR1 (0.44) | GAARXFP1NPSR1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |