Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966061 | 0.84 | CNR1 (0.52) | GLSL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL5863497 | 0.83 | TDP1 (0.51) | MEN1KMT2AG6PDTLR9KAT2B | |
| SCHEMBL14966684 | 0.82 | GLS (0.45) | GLSL3MBTL1MEN1KMT2AMIF | |
| SCHEMBL14966246 | 0.81 | GLS (0.44) | GLSL3MBTL1MEN1KMT2AMIF | |
| SCHEMBL14965963 | 0.80 | L3MBTL1 (0.50) | GLSL3MBTL1MEN1KMT2AG6PD | |
| SCHEMBL28899217 | 0.78 | MAPT (0.52) | MEN1KMT2AMAPTKAT2B | |
| SCHEMBL14965797 | 0.78 | CNR2 (0.42) | GLSMEN1KMT2AG6PDTLR9 | |
| SCHEMBL5864200 | 0.77 | CFTR (0.48) | GLSL3MBTL1G6PDTLR9POLB | |
| SCHEMBL5864274 | 0.77 | PDE5A (0.43) | GLSL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL14966025 | 0.74 | MEN1 (0.44) | GLSL3MBTL1MEN1KMT2AG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983606-A | Pharmaceutically-active phthalazine compounds | ZAMBON GROUP S.P.A. (IT) | 1991-01-08 | — | — | US | disclosed |