Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875561 | 0.92 | MEN1 (0.61) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL9875419 | 0.87 | LMNA (0.54) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL5756614 | 0.85 | SRD5A2 (0.46) | MEN1KMT2AHTTALDH1A1TDP1 | |
| SCHEMBL6202230 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL9875197 | 0.79 | SRC (0.42) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9874612 | 0.78 | MEN1 (0.62) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL5758160 | 0.78 | MEN1 (0.52) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6198849 | 0.76 | EGLN1 (0.51) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL10991178 | 0.75 | MEN1 (0.64) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL529310 | 0.75 | MAPT (0.51) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |