Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874612 | 0.91 | MEN1 (0.62) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL9874420 | 0.87 | MEN1 (0.51) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL2721434 | 0.83 | LMNA (0.58) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9872120 | 0.83 | LMNA (0.58) | LMNAMEN1KMT2AALDH1A1MAPK10 | |
| Hydrochloric Acid SCHEMBL9872122 | 0.81 | LMNA (0.60) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9875438 | 0.81 | LMNA (0.56) | LMNAMEN1KMT2AALDH1A1MAPK10 | |
| SCHEMBL2718832 | 0.81 | LMNA (0.56) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL9872577 | 0.81 | MEN1 (0.44) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9875561 | 0.78 | MEN1 (0.61) | LMNAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL529310 | 0.76 | MAPT (0.51) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |