SCHEMBL9874429

SCHEMBL9874429

O=C1CCC2(CCC(=O)N2c2ccc(Oc3cccc(O)c3)cc2)N1c1ccc(Oc2cccc(O)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 11/20 0.52
MMP2 P08253 6/20 0.50
MMP3 P08254 6/20 0.50
MMP9 P14780 6/20 0.50
BRD4 O60885 1/20 0.41
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SCN9A Q15858 1/20 0.37
AKR1C3 P42330 1/20 0.37
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9874462 0.86 MMP13 (0.50) MMP13MMP2MMP3MMP9MEN1
SCHEMBL9729935 0.84 MMP13 (0.66) MMP13MMP2MMP3MMP9ALDH1A1
SCHEMBL10391857 0.81 ESR1 (0.41) MMP13MEN1KMT2AALDH1A1POLB
SCHEMBL9676223 0.80 MEN1 (0.44) MMP13MEN1KMT2AALDH1A1POLB
SCHEMBL10465599 0.79 MMP13 (0.47) MMP13MMP2MMP3MMP9MEN1
SCHEMBL9874441 0.77 ALDH1A1 (0.52) MMP13MMP2MMP3MMP9ALDH1A1
SCHEMBL10392048 0.74 MMP13 (0.50) MMP13MMP2MMP3MMP9MEN1
SCHEMBL9773502 0.73 MMP13 (0.38) MMP13MMP2MMP3MMP9KMT2A
SCHEMBL21995539 0.73 CRBN (0.52) MMP13BRD4SCN9AAKR1C3ALDH1A1
SCHEMBL31674505 0.73 CRBN (0.52) MMP13BRD4SCN9AAKR1C3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5001213-A Thermosetting resin compositions SHELL OIL COMPANY (US) 1991-03-19 US disclosed
US-4933423-A Thermosetting resin compositions SHELL OIL COMPANY (US) 1990-06-12 US disclosed