Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 13/20 | 0.66 |
| ▸ | MMP2 | P08253 | 6/20 | 0.66 |
| ▸ | MMP3 | P08254 | 6/20 | 0.66 |
| ▸ | MMP9 | P14780 | 6/20 | 0.66 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874462 | 0.86 | MMP13 (0.50) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9874429 | 0.84 | MMP13 (0.52) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9730386 | 0.84 | MMP13 (0.59) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9730368 | 0.81 | MMP13 (0.63) | MMP13MMP2MMP3MMP9MGLL | |
| SCHEMBL12336942 | 0.80 | MMP13 (1.00) | MMP13MMP2MMP3MMP9 | |
| SCHEMBL10392048 | 0.79 | MMP13 (0.50) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9874441 | 0.77 | ALDH1A1 (0.52) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL10466906 | 0.77 | ALDH1A1 (0.45) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9734487 | 0.76 | ALDH1A1 (0.50) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9730839 | 0.74 | MMP13 (0.52) | MMP13MMP2MMP3MMP9MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093499-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |