Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874471 | 1.00 | HSD11B1 (0.46) | HSD11B1NPC1RAB9AATMKMT2A | |
| SCHEMBL9874972 | 0.87 | HSD11B1 (0.47) | HSD11B1ALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL9873876 | 0.87 | HSD11B1 (0.47) | HSD11B1ALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL9872319 | 0.87 | SLC6A1 (0.54) | KDM4EALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL9872312 | 0.87 | SLC6A1 (0.54) | KDM4EALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL9872738 | 0.86 | GAA (0.47) | KMT2AKDM4EMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7844617 | 0.86 | HSD11B1 (0.48) | HSD11B1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL9872741 | 0.86 | GAA (0.47) | KMT2AKDM4EMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL9875176 | 0.83 | ALDH1A1 (0.50) | HSD11B1ALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL9875180 | 0.83 | ALDH1A1 (0.50) | HSD11B1ALDH1A1L3MBTL1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |