Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875533 | 0.76 | KDM4E (0.46) | TSHRALDH1A1ACHE | |
| SCHEMBL9874533 | 0.71 | — | — | |
| Velnacrine SCHEMBL194467 | 0.71 | CYP1A2 (1.00) | CYP1A2CYP2C9TSHRALDH1A1NR3C1 | |
| SCHEMBL9875693 | 0.70 | CYP1A2 (0.65) | CYP1A2CYP2C9TSHRALDH1A1NR3C1 | |
| SCHEMBL9875581 | 0.68 | PABPC1 (0.65) | — | |
| SCHEMBL27918398 | 0.68 | CYP1A2 (0.48) | CYP1A2CYP2C9TSHRALDH1A1NR3C1 | |
| SCHEMBL9874125 | 0.66 | — | — | |
| SCHEMBL10286807 | 0.65 | ACHE (0.65) | CYP1A2CYP2C9TSHRALDH1A1NR3C1 | |
| Velnacrine SCHEMBL50846 | 0.65 | TSHR (0.83) | CYP1A2CYP2C9TSHRALDH1A1NR3C1 | |
| Suronacrine SCHEMBL975421 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4695573-A | COGNITION ACTIVATORS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-09-22 | — | — | US | claimed |
| EP-2681554-B1 | BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR | BECTON DICKINSON CO (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9459187-B2 | Blood collection device containing lysophospholipase inhibitor | BECTON, DICKINSON AND COMPANY (US) | 2016-10-04 | — | — | US | disclosed |
| CN-103477224-B | Blood collection device containing lysophospholipase inhibitor | BECTON, DICKINSON AND CO. (US) | 2015-12-23 | — | — | CN | disclosed |
| CN-104244902-A | Sample collection devices with blood stabilizing agents | BECTON DICKINSON CO | 2014-12-24 | — | — | CN | disclosed |
| EP-2809289-A1 | SAMPLE COLLECTION DEVICES WITH BLOOD STABILIZING AGENTS | Becton, Dickinson and Company (US) | 2014-12-10 | — | — | EP | disclosed |
| US-20140030754-A1 | BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR | BECTON, DICKINSON AND COMPANY (US) | 2014-01-30 | — | — | US | disclosed |
| CN-103477224-A | Blood collection device containing lysophospholipase inhibitor | BECTON DICKINSON CO | 2013-12-25 | — | — | CN | disclosed |
| CN-203203992-U | Blood collection device containing lysophospholipase inhibitor | BECTON DICKINSON CO | 2013-09-18 | — | — | CN | disclosed |
| US-20130209985-A1 | SAMPLE COLLECTION DEVICES WITH BLOOD STABILIZING AGENTS | BECTON, DICKINSON AND COMPANY | 2013-08-15 | — | — | US | disclosed |
| WO-2013116702-A1 | SAMPLE COLLECTION DEVICES WITH BLOOD STABILIZING AGENTS | BECTON, DICKINSON AND COMPANY (US) | 2013-08-08 | — | — | WO | disclosed |
| EP-0179383-B1 | 9-AMINO-1,2,3,4-TETRAHYDROACRIDIN-1-OL AND RELATED COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4839364-A | ALZHEIMER*S DISEASE; CHOLINESTERASE INHIBITORS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-13 | — | — | US | disclosed |
| US-4835275-A | Method of preparing 9-amino-1,2,3,4,-tetrahydroacridin-1-ones and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-05-30 | — | — | US | disclosed |
| US-4754050-A | COGNITION ACTIVATORS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-06-28 | — | — | US | disclosed |
| US-4695573-A | COGNITION ACTIVATORS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-09-22 | — | — | US | disclosed |
| EP-0179383-A2 | 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-04-30 | — | — | EP | disclosed |